Effect of zotepine on fenfluramine-induced hyperthermia in rats.
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چکیده
منابع مشابه
Effect of magnesium sulfate on hyperthermia and pentylen-tetrazol-induced seizure in developing rats
Objective(s): Febrile seizures (FS) are the most common type of convulsive events among children. Its prevalence has been estimated to be 2-5% in children between 3 months and 5 years old. Also, blood and CSF magnesium levels have been demonstrated to be reduced in children with FS. This study investigates the effect of MgSo4 pretreatment on the behaviors caused by hyperthermia (HT) and effect ...
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Introduction: Febrile seizures are the most common seizure disorder in childhood and its prevalence is estimated to be 2 to 5 percent. There is a relationship between the use of corticosteroids and seizures. This study investigated the effects of dexamethasone pretreatment on convulsive behavior caused by hyperthermia. Methods: In this study, 24 rats aged 19-20 days were divided into 3 group...
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Oxidative and/or bioenergetic stress is thought to contribute to the mechanism of neurotoxicity of amphetamine derivatives, e.g., 3,4-methylenedioxymethamphetamine (MDMA). In the present study, the effect of MDMA on brain energy regulation was investigated by examining the effect of MDMA on brain glycogen and glucose. A single injection of MDMA (10-40 mg/kg, s.c.) produced a dose-dependent decr...
متن کاملCHANGES IN BIOCHEMICAL PARAMETERS OF CARBOHYDRATE METABOLISM FOLLOWING FENFLURAMINE ADMINIS TRATION IN RATS
Fenfluramine, an anorexigenic agent, is widely used in the treatment of obesity. Besides its anorectic effect, it may also have some effects on general metabolism with the consequence of weight loss. In this study, the effect of fenfluramine on the concentrations of some parameters related to carbohydrate metabolism was investigated. It was shown that the serum insulin level was reduced by ...
متن کاملThe ameliorative potential of ethanolic extract of propolis on hematotoxicity and structural neuronal damage in hyperthermia-exposed rats
Objective(s): Hyperthermia is one of the most common environmental stressors that affect multi-biological systems in the body including the central nervous system as well as the hematopoietic organs. The objective of the present study was to investigate the protective role of ethanolic extract of propolis (EEP) on some selective stress markers, hematological, biochemical, and histopathological ...
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عنوان ژورنال:
- Japanese journal of pharmacology
دوره 34 2 شماره
صفحات -
تاریخ انتشار 1984